Pep-Talk
Tb-500 vial

Tb-500

Educational resource. Not medical advice. No dosing or instructions.

Safety grade
6/10
High
Also known as
tb 500TB500Thymosin Beta-4 fragmenttbtb 500 peptidetb-500tb500
AA sequence
Not available yet.
What it is
TB-500 is a peptide product marketed in recovery contexts, often linked to thymosin beta-4 biology. Many claims rely on preclinical data; human outcome evidence for TB-500 as sold is limited.
Refs: E1

Why people are interested in this peptide and how it is commonly discussed in real-world wellness, rehabilitation, and athletic communities.

Why people are interested
  • a peptide product marketed in recovery contexts, often linked to thymosin beta-4 biology
  • tendon and ligament recovery support
  • soft tissue healing after overuse or injury
  • return-to-training support during rehab
  • joint comfort and mobility support
  • interest in tissue repair pathways

TB-500 is marketed as a recovery peptide linked to thymosin beta-4 fragments. Real-world use centers on soft-tissue recovery claims; human evidence is limited.

Common reasons people consider it

  • soft-tissue recovery discussions (anecdotal, evidence limited)
  • general “inflammation control” claims in some communities (often overstated)
  • sometimes grouped with other injury-healing compounds in recovery culture

Most commonly reported downsides

  • fatigue
  • headache
  • nausea

Rare but important symptoms to watch for

These are uncommon, but if they occur, stop and seek medical care.

  • severe allergic reaction symptoms (hives, facial swelling, trouble breathing)
  • persistent chest pain, fainting, or severe shortness of breath

Who should be cautious

  • people with active cancer or a high cancer-risk history (tissue-growth signaling context)
  • pregnant or breastfeeding individuals
  • adolescents (limited evidence and developmental uncertainty)
  • anyone using unverified sources (contamination and mislabeling risk)

Interactions summarize known or plausible ways this peptide may intersect with medications, supplements, or physiologic states. Use this as a risk-awareness map: what to ask about, what to watch for, and what deserves a clinician conversation.

Medication classes
None
Supplement classes
Other peptides
None
Developmental / Adolescent risk
Because TB-500 claims are often preclinical and safety is not well characterized, adolescents should treat uncertainty as meaningful risk, especially given real-world sourcing variability.
Refs: E1
PMC · Grade: animal · Year: 2014
Thymosin beta-4 biology and tissue repair (review; context for claims)
Broad review of thymosin beta-4 biology; supports mechanistic plausibility in animals but does not establish TB-500 outcomes in humans.
TB-500 is not an approved therapeutic drug. Evidence for many recovery claims is primarily preclinical; human evidence for TB-500 specifically is limited. Unapproved peptide commonly discussed in recovery contexts. Often conflated with Thymosin Beta-4 (Tβ4) biology; products vary and claims frequently exceed evidence.
Pep-Talk is informational only and not medical advice. We make no warranties and are not liable for actions you take. You are responsible for your decisions and outcomes.

Community notes

Educational discussion only. No dosing, protocols, schedules, or instructions. Submissions are moderated before appearing.
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