Humanin
Educational resource. Not medical advice. No dosing or instructions.
Safety grade
5/10
Moderate
Also known as
hnhumanin
AA sequence
Not available yet.
No overview has been added yet.
Why people are interested in this peptide and how it is commonly discussed in real-world wellness, rehabilitation, and athletic communities.
Why people are interested
- Pep-Talk curation pending: we’re reviewing the evidence and will expand this section soon.
- general recovery and resilience interest (anecdotal)
- common biohacker curiosity due to community reports
- interest in mechanisms suggested by early evidence
- used in goal-based stacking discussions (anecdotal)
- exploration in wellness communities despite evidence limits
Use cases (real-world)
These are the most common real-world reasons people look into this peptide, plus the context that tends to matter most (quality, expectations, and safety).
research interest in cellular stress and mitochondrial signaling
neuroprotection themes in early-stage literature discussions
often framed as longevity support (claims frequently exceed evidence)
Humanin is discussed for mitochondrial and neuroprotection themes, but robust human outcomes are not established. Treat it as early-stage science with uncertain real-world benefit.
Common reasons people consider it
- research interest in cellular stress and mitochondrial signaling
- neuroprotection themes in early-stage literature discussions
- often framed as longevity support (claims frequently exceed evidence)
Most commonly reported downsides
- headache
- nausea
- fatigue
Rare but important symptoms to watch for
These are uncommon, but if they occur, stop and seek medical care.
- chest pain, fainting, or severe shortness of breath
- severe allergic reaction symptoms (hives, facial swelling, trouble breathing)
Who should be cautious
- people with significant cardiovascular disease
- people with cancer history or active malignancy concern (growth/survival signaling context)
- pregnant or breastfeeding individuals
- adolescents (limited human evidence and long-term uncertainty)
Interactions summarize known or plausible ways this peptide may intersect with medications, supplements, or physiologic states. Use this as a risk-awareness map: what to ask about, what to watch for, and what deserves a clinician conversation.
Interaction summary
Interactions here are category flags — they’re meant to help you ask better questions and avoid obvious conflicts. They are not a dosing guide.
No interaction classes are tagged yet for this peptide. That may mean ‘not reviewed’ rather than ‘no interactions.’
If you’re on cardiovascular, anticoagulant/antiplatelet, serotonergic, or immunomodulating meds/supplements, treat uncertainty as a reason to slow down and verify with a clinician.
Medication classes
None
Supplement classes
None
Other peptides
None
Developmental risk is flagged due to limited adolescent data and uncertain long-term effects. Endocrine, growth, neurodevelopmental, and metabolic setpoints may be sensitive to perturbation. This section is descriptive only; uncertainty is explicitly acknowledged.
No curated human clinical sources have been added yet.
Pep-Talk curation pending: we’re reviewing the evidence and will expand this section soon.
Pep-Talk is informational only and not medical advice. We make no warranties and are not liable for actions you take. You are responsible for your decisions and outcomes.
Community notes
Educational discussion only. No dosing, protocols, schedules, or instructions. Submissions are moderated before appearing.
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